GAMBIER — How can we make scientific innovations accessible at the earliest stages of discovery? Dr. James E. Bradner, president of the Novartis Institutes for BioMedical Research, shares his insight in an address titled “Open Science for Undruggable Targets” on Tuesday, at 7 p.m., in Higley Hall Auditorium, 202 N. College Road.

Bradner is known widely for advocating open-source science, a collaborative approach to scientific discovery that champions the free exchange of information, methods and materials. After breaking new ground with a molecule that prompts cancer cells to “forget” they are cancer cells, Bradner and his research team published its structure and sent samples to labs around the world to speed the development of cancer-fighting drugs.

“For years, drug discovery has been a dark art performed behind closed doors with the shades pulled,” Bradner told The Atlantic in a 2012 interview. “I would be greatly satisfied if the example of this research contributed to a change in the culture of drug discovery.”

Prior to joining Novartis, Bradner served as an associate professor on the research faculty of Harvard Medical School and as an attending physician in stem cell transplantation within the Department of Medical Oncology at the Dana-Farber Cancer Institute. He has authored more than 30 U.S. patent applications and has founded five biotechnology companies. Bradner has published more than 200 scientific publications in journals including Nature, Science and Cell, among others. Since 2010, his lab has shared 15 different compounds with more than 450 laboratories worldwide.

Bradner earned a bachelor’s degree from Harvard University and his medical degree from the University of Chicago Medical School. He completed his residency in medicine at Brigham and Women’s Hospital, a fellowship in medical oncology and hematology at the Dana-Farber Cancer Institute, and postdoctoral training in chemistry and chemical biology at Harvard University.

This event is free and open to the public. Bradner’s visit is sponsored by Kenyon’s Faculty Lectureships program.

 

 

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